Changement climatique - Recherche française (avec laboratoires CNRS) - 2010-2015


DengueTools: innovative tools and strategies for the surveillance and control of dengue

Publication Year


  • Wilder-Smith, Annelies
  • Renhorn, Karl-Erik
  • Tissera, Hasitha
  • Abu Bakar, Sazaly
  • Alphey, Luke
  • Kittayapong, Pattamaporn
  • Lindsay, Steve
  • Logan, James
  • Hatz, Christoph
  • Reiter, Paul
  • Rocklov, Joacim
  • Byass, Peter
  • Louis, Valerie R.
  • Tozan, Yesim
  • Massad, Eduardo
  • Tenorio, Antonio
  • Lagneau, Christophe
  • L'Ambert, Gregory
  • Brooks, David
  • Wegerdt, Johannah
  • Gubler, Duane
GLOBAL HEALTH ACTION Volume: 5 Pages: 1-9 Published: 2012

Dengue fever is a mosquito-borne viral disease estimated to cause about 230 million infections worldwide every year, of which 25,000 are fatal. Global incidence has risen rapidly in recent decades with some 3.6 billion people, over half of the world's population, now at risk, mainly in urban centres of the tropics and subtropics. Demographic and societal changes, in particular urbanization, globalization, and increased international travel, are major contributors to the rise in incidence and geographic expansion of dengue infections. Major research gaps continue to hamper the control of dengue. The European Commission launched a call under the 7th Framework Programme with the title of 'Comprehensive control of Dengue fever under changing climatic conditions'. Fourteen partners from several countries in Europe, Asia, and South America formed a consortium named 'DengueTools' to respond to the call to achieve better diagnosis, surveillance, prevention, and predictive models and improve our understanding of the spread of dengue to previously uninfected regions (including Europe) in the context of globalization and climate change. The consortium comprises 12 work packages to address a set of research questions in three areas: Research area 1: Develop a comprehensive early warning and surveillance system that has predictive capability for epidemic dengue and benefits from novel tools for laboratory diagnosis and vector monitoring. Research area 2: Develop novel strategies to prevent dengue in children. Research area 3: Understand and predict the risk of global spread of dengue, in particular the risk of introduction and establishment in Europe, within the context of parameters of vectorial capacity, global mobility, and climate change. In this paper, we report on the rationale and specific study objectives of 'DengueTools'. DengueTools is funded under the Health theme of the Seventh Framework Programme of the European Community, Grant Agreement Number: 282589 Dengue Tools.

Author Keyword(s)
  • dengue
  • dengue control
  • dengue diagnostics
  • economic evaluation
  • entomology
  • climate change
  • early warning systems
  • risk mapping
  • surveillance
  • globalization
KeyWord(s) Plus
ESI Discipline(s)
  • Clinical Medicine
  • Social Sciences
Web of Science Category(ies)
  • Public, Environmental & Occupational Health

[Wilder-Smith, Annelies; Renhorn, Karl-Erik; Rocklov, Joacim; Byass, Peter; Wegerdt, Johannah] Umea Univ, Dept Publ Hlth & Clin Med Epidemiol & Global Hlth, SE-90185 Umea, Sweden; [Tissera, Hasitha] Minist Hlth, Epidemiol Unit, Colombo, Sri Lanka; [Abu Bakar, Sazaly] Univ Malaya, TIDREC, WHO Collaborating Ctr Arbovirus, Kuala Lumpur, Malaysia; [Alphey, Luke] Oxitec Ltd, Oxford, England; [Kittayapong, Pattamaporn] Mahidol Univ, Fac Sci, Dept Biol, Ctr Excellence Vectors & Vector Borne Dis, Bangkok 10400, Thailand; [Lindsay, Steve; Logan, James] London Sch Hyg & Trop Med, Dept Dis Control, London WC1, England; [Hatz, Christoph] Swiss Trop & Publ Hlth Inst, Dept Med Serv, Basel, Switzerland; [Reiter, Paul] Inst Pasteur, Insects & Infect Dis Unit, Paris, France; [Wilder-Smith, Annelies; Louis, Valerie R.; Tozan, Yesim] Univ Heidelberg, Sch Med, Inst Publ Hlth, Heidelberg, Germany; [Tozan, Yesim] Boston Univ, Sch Publ Hlth, Dept Int Hlth, Boston, MA USA; [Massad, Eduardo] Univ Sao Paulo, Sao Paulo, Brazil; [Tenorio, Antonio] Inst Salud Carlos III, Madrid, Spain; [Lagneau, Christophe; L'Ambert, Gregory] Entente Interdept Demousticat Littoral Mediterran, Montpellier, France; [Brooks, David] TwistDx Ltd, Cambridge, England; [Gubler, Duane] DUKE NUS, Grad Sch Med, Singapore, Singapore

Reprint Adress

Wilder-Smith, A (reprint author), Umea Univ, Dept Publ Hlth & Clin Med Epidemiol & Global Hlth, SE-90185 Umea, Sweden.

  • Brazil
  • France
  • Germany
  • Malaysia
  • Singapore
  • Spain
  • Sri Lanka
  • Sweden
  • Switzerland
  • Thailand
  • United Kingdom
  • United States
CNRS - Adress(es)
  • Hôtes, vecteurs et agents infectieux : biologie et dynamique, URA3012
Accession Number
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